Medicine by Design-funded researchers generate cells that will impact treatments for bile duct disorders as a result of cystic fibrosis

Newly-generated cells may lead to a deeper understanding of bile duct disease and be a powerful tool for finding new treatments.

By |2021-11-18T11:06:55-05:00November 16th, 2021|Categories: News, Research Publication|Tags: , , , , , |

Medicine by Design-funded research finds transplanting insulin-producing cells with blood vessels may help reverse diabetes

Researchers have engineered a new method to improve the survival and potency of cell transplants to treat diabetes.

By |2021-09-07T16:21:04-04:00September 7th, 2021|Categories: News, Research Publication|Tags: , , |

Medicine by Design-funded research uncovers important gap in knowledge of tissue development

Computational biology study found two fundamental mechanisms involved in the cell play important roles and may help better control cells used in regenerative medicine applications

Medicine by Design-funded scientists discover a new stem cell property that could enhance life-saving blood stem cell transplants

Researchers say the findings lay groundwork that could lead to methods for expanding stem cell numbers from donated cord blood biobanks to improve availability for people with leukemia.

New research shows diabetes drug could provide brain protection to children who get radiation for brain tumours

Thanks to funding from Medicine by Design, a University of Toronto scientist and her team are closer to finding a way to protect the brain from damage for children who must be treated with cranial radiation.

Mapping out the mystery of blood stem cells

Using state-of-the art sequencing technology, Medicine by Design-funded scientists have revealed how stem cells are able to generate new blood cells throughout our life, and how these same cellular mechanisms can evade chemotherapy to survive and cause relapse many years later.

By |2021-06-02T16:07:11-04:00November 25th, 2020|Categories: News, Research, Research Publication|Tags: , , |

Medicine by Design-funded researchers develop a new tool for scooping contents of individual cells from their local environment

Scientists can now select individual cells from their local environment & study their molecular contents. The new tool will enable a deeper study of stem cells and other rare cell types for diagnostics & therapy.

Medicine by Design-funded researchers develop cell injection technique that could help reverse vision loss

The technique could point the way toward new treatments with the potential to reverse forms of vision loss that are currently incurable.

By |2021-06-02T16:09:58-04:00August 19th, 2020|Categories: News, Research Publication|Tags: , , , , |

Critical planning for regenerative medicine therapies needs to happen now to ensure smooth adoption into health system, paper urges

Data generation, evidence of clinical effectiveness, cost and social values among the key considerations

By |2021-06-02T16:10:36-04:00August 13th, 2020|Categories: News, Research Publication|Tags: , , , , , , |

U of T and SickKids researchers demonstrate drug stimulation of neural stem cell repair leads to promising impact on treatment of childhood brain injury in survivors of brain cancer

Cross-species study shows that Type 2 diabetes drug metformin could change the way childhood brain injury is treated

Medicine by Design-funded team uses stem cells to grow functional blood vessel cells found in the liver

Discovery to provide insights into liver development and disease progression

Researchers delay onset of amyotrophic lateral sclerosis (ALS) in laboratory models

A team of researchers led by scientists at the University of Toronto has delayed the onset of amyotrophic lateral sclerosis (ALS) in mice. They are cautiously optimistic that this research, which was funded in part by a Medicine by Design 2018 New Ideas Award, combined with other clinical advances, points to a potential treatment for ALS in humans.

By |2021-06-02T16:12:20-04:00April 22nd, 2020|Categories: News, Research Publication|Tags: , , , |

Genome editing just got more versatile thanks to a new technology developed by Medicine by Design-funded investigators at U of T

Scientists can now edit multiple sites in the genome at the same time to learn how different DNA stretches co-operate in health and disease.

By |2021-06-02T16:12:57-04:00March 16th, 2020|Categories: News, Research Publication|
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