Medicine by Design-funded scientists discover a new stem cell property that could enhance life-saving blood stem cell transplants

Researchers say the findings lay groundwork that could lead to methods for expanding stem cell numbers from donated cord blood biobanks to improve availability for people with leukemia.

Mapping out the mystery of blood stem cells

Using state-of-the art sequencing technology, Medicine by Design-funded scientists have revealed how stem cells are able to generate new blood cells throughout our life, and how these same cellular mechanisms can evade chemotherapy to survive and cause relapse many years later.

By |2021-06-02T16:07:11-04:00November 25th, 2020|Categories: News, Research, Research Publication|Tags: , , |

Medicine by Design-funded researchers develop a new tool for scooping contents of individual cells from their local environment

Scientists can now select individual cells from their local environment & study their molecular contents. The new tool will enable a deeper study of stem cells and other rare cell types for diagnostics & therapy.

Medicine by Design seeds two strategic projects: An international partnership with the University of Cambridge and a new forum that will foster collaboration between clinicians, scientists and industry

$300,000 investment will accelerate new therapies and create new research tools.

U of T and SickKids researchers demonstrate drug stimulation of neural stem cell repair leads to promising impact on treatment of childhood brain injury in survivors of brain cancer

Cross-species study shows that Type 2 diabetes drug metformin could change the way childhood brain injury is treated

Toronto investigators part of international team receiving $4-million (U.S.) award from Chan Zuckerberg Initiative

The project, part of the Human Cell Atlas, seeks to build a more complete map of the human liver and is a “direct extension” of the work the Toronto team has already done with support from Medicine by Design

Medicine by Design researchers featured in Science story on reprogramming cells into neurons to treat brain injury

Cindi Morshead and Maryam Faiz talk about the work they presented at the annual meeting of the Society for Neuroscience.

By |2020-04-24T12:45:39-04:00November 14th, 2018|Categories: New Ideas, News, Research, Team Projects|Tags: , , |

How the first “map” of the human liver came together through a collaboration sown by Medicine by Design

Believed to be the first time a human organ has been charted at the single-cell level, the research illuminates the basic biology of the liver in ways that could eventually increase the success of transplant surgery and enable viable regenerative medicine treatments for liver disease.

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