Pioneering patient-guided study helps map rare liver disease
Innovative study unveils rare liver disease secrets
Medicine by Design-funded scientists discover a new stem cell property that could enhance life-saving blood stem cell transplants
Researchers say the findings lay groundwork that could lead to methods for expanding stem cell numbers from donated cord blood biobanks to improve availability for people with leukemia.
Mapping out the mystery of blood stem cells
Using state-of-the art sequencing technology, Medicine by Design-funded scientists have revealed how stem cells are able to generate new blood cells throughout our life, and how these same cellular mechanisms can evade chemotherapy to survive and cause relapse many years later.
Medicine by Design-funded researchers develop a new tool for scooping contents of individual cells from their local environment
Scientists can now select individual cells from their local environment & study their molecular contents. The new tool will enable a deeper study of stem cells and other rare cell types for diagnostics & therapy.
Medicine by Design seeds two strategic projects: An international partnership with the University of Cambridge and a new forum that will foster collaboration between clinicians, scientists and industry
$300,000 investment will accelerate new therapies and create new research tools.
U of T and SickKids researchers demonstrate drug stimulation of neural stem cell repair leads to promising impact on treatment of childhood brain injury in survivors of brain cancer
Cross-species study shows that Type 2 diabetes drug metformin could change the way childhood brain injury is treated
Medicine by Design researchers enlist tiny biomagnets for faster drug discovery
A new platform brings together genome editing with magnetic cell sorting to reveal new drug targets for cancer and regenerative medicine
A diabetes drug promotes brain repair — but only in females, U of T study shows
Accounting for sex differences could be key for the development of better treatments as drug shows promise for brain repair in females only
Toronto investigators part of international team receiving $4-million (U.S.) award from Chan Zuckerberg Initiative
The project, part of the Human Cell Atlas, seeks to build a more complete map of the human liver and is a “direct extension” of the work the Toronto team has already done with support from Medicine by Design
Technion professor to become first Medicine by Design Scholar in Residence
Professor Shulamit Levenberg will serve as Medicine by Design’s first Scholar in Residence from July 15 to August 15, 2019.
Medicine by Design researchers featured in Science story on reprogramming cells into neurons to treat brain injury
Cindi Morshead and Maryam Faiz talk about the work they presented at the annual meeting of the Society for Neuroscience.
Medicine by Design-funded researchers devise new strategy to improve the safety of cell therapies
Finding inspiration from an unlikely source, a team led by Andras Nagy at Sinai Health System has an answer for one of the most pressing questions in cell therapy: how to ensure its safety
How the first “map” of the human liver came together through a collaboration sown by Medicine by Design
Believed to be the first time a human organ has been charted at the single-cell level, the research illuminates the basic biology of the liver in ways that could eventually increase the success of transplant surgery and enable viable regenerative medicine treatments for liver disease.
Medicine by Design researchers clear hurdles toward robust supply of stem cells for research and therapy
Paper identifies new combination of factors that allow scientists to grow stem cells in lab on much larger scale than previously possible
New video highlights importance of collaboration and working across disciplines in regenerative medicine
Hear from some of the investigators who make up the Medicine by Design community