Making a bile duct
The University of Toronto's Axel Guenther’s lab has developed collagen tubes that hold potential to be developed into lab-grown bile ducts, with the aim of being able to replace this part of the organ in a patient. Read more.
Studying cystic fibrosis-linked liver disease
Christine Bear's lab at The Hospital for Sick Children (SickKids), along with other labs, is working on treating cystic fibrosis-linked liver disease with regenerative medicine approaches. Read more.
Moving liver cell therapy toward the clinic
Shinichiro Ogawa, a scientist at the McEwen Stem Cell Institute, University Health Network, is focused on the early-stage translation of the liver cells from experiment to clinical application. Read more.
Medicine by Design symposium panel and announcement put a focus on intentional innovation through partnerships
The symposium — themed “Intentional Innovation” — attracted more than 750 registrants
Medicine by Design and CCRM announce strategic alliance to bolster Canada’s globally-leading position in regenerative medicine
This alliance is set to unlock Toronto's potential as a globally-leading ecosystem for regenerative medicine
Research highlight: Medicine by Design-funded work offers insight into immune cell signalling
Study offers new insights into the role of macrophages
Five ways Medicine by Design is transforming the treatment of brain diseases
Medicine by Design-funded researchers are leading the way in ground-breaking neurological research
Reprogramming cells in the brain with a gene therapy
A Medicine by Design team is working on reprogramming brain cells — a strategy that has demonstrated brain repair in animal models of stroke. "Think of it as a bespoke strategy for brain repair,” says Maryam Faiz, one of the team's researchers. Read more.
Helping the brain repair itself
Stem cells can repair tissues and organs damaged by acute injury, genetic disease or the aging process. Freda Miller leads a team that is tackling the question of how to activate stem cells to repair the brain on demand. Read more.
“Mini brains” — or organoids — to model disease
A Medicine by Design team lead by Jeff Wrana aims to use organoids to gain unique insights into the human-specific aspects of signaling networks associated with conditions such as autism. Read more.
Electrical stimulation for brain repair
A project led by Cindi Morshead is investigating electrical stimulation's promise for neural repair through promoting neuroplasticity and facilitating neural regeneration. Read more.
An integrated approach to treating blindness
An interdisciplinary team of scientists led by Molly Shoichet is working on a ground-breaking research project to restore vision using retinal stem cells. Read more.
Technology supported through Medicine by Design’s Grand Questions Program automates the study of cell behaviour to accelerate regenerative medicine treatments
New technology allows researchers to watch single cell behaviour at scale
Summer by Design: 10 highlights from the program
The eight-day intensive program at the University of Toronto hosted PhD students and post-doctoral fellows from around the world.
Summer by Design cohort from 17 global institutions to come to U of T to learn about the commercialization of regenerative medicine
The program began in 2016 and is run by Medicine by Design in partnership with CCRM, Rotman School of Management and the Stem Cell Network