Medicine by Design-funded research finds transplanting insulin-producing cells with blood vessels may help reverse diabetes
Researchers have engineered a new method to improve the survival and potency of cell transplants to treat diabetes.
Medicine by Design-funded research uncovers important gap in knowledge of tissue development
Computational biology study found two fundamental mechanisms involved in the cell play important roles and may help better control cells used in regenerative medicine applications
Medicine by Design-funded scientists discover a new stem cell property that could enhance life-saving blood stem cell transplants
Researchers say the findings lay groundwork that could lead to methods for expanding stem cell numbers from donated cord blood biobanks to improve availability for people with leukemia.
New research shows diabetes drug could provide brain protection to children who get radiation for brain tumours
Thanks to funding from Medicine by Design, a University of Toronto scientist and her team are closer to finding a way to protect the brain from damage for children who must be treated with cranial radiation.
Mapping out the mystery of blood stem cells
Using state-of-the art sequencing technology, Medicine by Design-funded scientists have revealed how stem cells are able to generate new blood cells throughout our life, and how these same cellular mechanisms can evade chemotherapy to survive and cause relapse many years later.
Medicine by Design-funded researchers develop a new tool for scooping contents of individual cells from their local environment
Scientists can now select individual cells from their local environment & study their molecular contents. The new tool will enable a deeper study of stem cells and other rare cell types for diagnostics & therapy.
Medicine by Design-funded researchers re-engineer enzyme that could help reverse damage from spinal cord injury and stroke
New version is more stable than the protein that occurs in nature, and could lead to new treatments for reversing nerve damage caused by traumatic injury or stroke.
Medicine by Design-funded researchers develop cell injection technique that could help reverse vision loss
The technique could point the way toward new treatments with the potential to reverse forms of vision loss that are currently incurable.
Critical planning for regenerative medicine therapies needs to happen now to ensure smooth adoption into health system, paper urges
Data generation, evidence of clinical effectiveness, cost and social values among the key considerations
U of T and SickKids researchers demonstrate drug stimulation of neural stem cell repair leads to promising impact on treatment of childhood brain injury in survivors of brain cancer
Cross-species study shows that Type 2 diabetes drug metformin could change the way childhood brain injury is treated
Medicine by Design-funded team uses stem cells to grow functional blood vessel cells found in the liver
Discovery to provide insights into liver development and disease progression
Researchers delay onset of amyotrophic lateral sclerosis (ALS) in laboratory models
A team of researchers led by scientists at the University of Toronto has delayed the onset of amyotrophic lateral sclerosis (ALS) in mice. They are cautiously optimistic that this research, which was funded in part by a Medicine by Design 2018 New Ideas Award, combined with other clinical advances, points to a potential treatment for ALS in humans.
Genome editing just got more versatile thanks to a new technology developed by Medicine by Design-funded investigators at U of T
Scientists can now edit multiple sites in the genome at the same time to learn how different DNA stretches co-operate in health and disease.
Researchers develop first electrochemical platform for cell-free synthetic biology
'We think we can really accelerate the field and its capacity to improve lives'
A diabetes drug promotes brain repair — but only in females, U of T study shows
Accounting for sex differences could be key for the development of better treatments as drug shows promise for brain repair in females only