People of Medicine by Design: Jesse Gillis
“By building up these cell atlases across healthy brains to serve as a reference, we’re now at a point where we can apply this knowledge to try to understand brain disorders.”
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Medicine by Design-funded TOGETHER network aims to make Ontario a hub for rare disease gene therapy
This blog post is just one of many in Signal’s seventh annual blog carnival discussing what hurdles need to be overcome for cell and gene therapies in clinical trials to reach the marketplace and whether the system is prepared.
Five ways Medicine by Design is transforming the treatment of brain diseases
Medicine by Design-funded researchers are leading the way in ground-breaking neurological research
Reprogramming cells in the brain with a gene therapy
A Medicine by Design team is working on reprogramming brain cells — a strategy that has demonstrated brain repair in animal models of stroke. "Think of it as a bespoke strategy for brain repair,” says Maryam Faiz, one of the team's researchers. Read more.
Helping the brain repair itself
Stem cells can repair tissues and organs damaged by acute injury, genetic disease or the aging process. Freda Miller leads a team that is tackling the question of how to activate stem cells to repair the brain on demand. Read more.
“Mini brains” — or organoids — to model disease
A Medicine by Design team lead by Jeff Wrana aims to use organoids to gain unique insights into the human-specific aspects of signaling networks associated with conditions such as autism. Read more.
Electrical stimulation for brain repair
A project led by Cindi Morshead is investigating electrical stimulation's promise for neural repair through promoting neuroplasticity and facilitating neural regeneration. Read more.
An integrated approach to treating blindness
An interdisciplinary team of scientists led by Molly Shoichet is working on a ground-breaking research project to restore vision using retinal stem cells. Read more.
Technology supported through Medicine by Design’s Grand Questions Program automates the study of cell behaviour to accelerate regenerative medicine treatments
New technology allows researchers to watch single cell behaviour at scale
Summer by Design: 10 highlights from the program
The eight-day intensive program at the University of Toronto hosted PhD students and post-doctoral fellows from around the world.
Summer by Design to welcome a 2023 cohort from 17 global institutions to U of T to learn about the business of regenerative medicine
The program began in 2016 and is run by Medicine by Design in partnership with CCRM, Rotman School of Management and the Stem Cell Network
Medicine by Design funds high-performing students from underrepresented groups in second year of Summer Student Research Program
Program is a partnership with the Research Application Support Initiative at the Temerty Faculty of Medicine and funds the student positions at $10k each
Five ways Medicine by Design is transforming the treatment of type 1 diabetes
Medicine by Design-funded researchers are leading the way in ground-breaking diabetes research
Medicine by Design invests $1 million in Convergent Working Group projects to integrate new strands of inquiry and expand its community across sectors
Seven new projects will focus on equity, commercialization policy, new regenerative medicine applications and more